A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen treatment in patients with diffuse cutaneous systemic sclerosis: I. oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease. Academic Article Article uri icon

Overview

MeSH

  • Administration, Oral
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Cattle
  • Disease Progression
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Severity of Illness Index
  • Treatment Outcome

MeSH Major

  • Collagen Type I
  • Immunosuppressive Agents
  • Scleroderma, Diffuse

abstract

  • To investigate the safety and efficacy of oral bovine type I collagen (CI) treatment in patients who have had diffuse cutaneous systemic sclerosis (dcSSc; scleroderma) for

publication date

  • June 2008

has subject area

  • Administration, Oral
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Cattle
  • Collagen Type I
  • Disease Progression
  • Double-Blind Method
  • Female
  • Humans
  • Immunosuppressive Agents
  • Male
  • Middle Aged
  • Scleroderma, Diffuse
  • Severity of Illness Index
  • Treatment Outcome

Research

keywords

  • Journal Article
  • Multicenter Study
  • Randomized Controlled Trial

Identity

Language

  • eng

PubMed Central ID

  • PMC4511098

Digital Object Identifier (DOI)

  • 10.1002/art.23501

PubMed ID

  • 18512816

Additional Document Info

start page

  • 1810

end page

  • 1822

volume

  • 58

number

  • 6