A multicenter, randomized, double-blind, placebo-controlled trial of oral type I collagen treatment in patients with diffuse cutaneous systemic sclerosis: I. Oral type I collagen does not improve skin in all patients, but may improve skin in late-phase disease Academic Article uri icon

Overview

MeSH Major

  • Collagen Type I
  • Immunosuppressive Agents
  • Scleroderma, Diffuse

abstract

  • Although the results from this trial did not meet the primary outcome goals, the findings from exploratory analyses indicated that CI treatment may benefit patients with late-phase dcSSc. This new treatment strategy and preliminary clinical observations in patients with dcSSc need to be corroborated.

publication date

  • June 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4511098

Digital Object Identifier (DOI)

  • 10.1002/art.23501

PubMed ID

  • 18512816

Additional Document Info

start page

  • 1810

end page

  • 22

volume

  • 58

number

  • 6