Oral prednisone taper following intravenous steroids fails to improve disability or recovery from relapses in multiple sclerosis
Multiple Sclerosis, Relapsing-Remitting
Recovery of Function
Our observations suggest that OPT following treatment with IVMP for an MS relapse does not lead to improved neurologic outcome after 12 months compared with treatment with IVMP only. Moreover, our findings raise concerns regarding the common practice of using OPT following IVMP. Further studies are indicated to validate our findings and minimize exposure to systemic corticosteroids, well known for systemic toxicity.