Oral prednisone taper following intravenous steroids fails to improve disability or recovery from relapses in multiple sclerosis Academic Article uri icon

Overview

MeSH Major

  • Anti-Inflammatory Agents
  • Methylprednisolone
  • Multiple Sclerosis, Relapsing-Remitting
  • Prednisone
  • Recovery of Function

abstract

  • Our observations suggest that OPT following treatment with IVMP for an MS relapse does not lead to improved neurologic outcome after 12 months compared with treatment with IVMP only. Moreover, our findings raise concerns regarding the common practice of using OPT following IVMP. Further studies are indicated to validate our findings and minimize exposure to systemic corticosteroids, well known for systemic toxicity.

publication date

  • July 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1111/j.1468-1331.2008.02146.x

PubMed ID

  • 18459972

Additional Document Info

start page

  • 677

end page

  • 80

volume

  • 15

number

  • 7