Nutrition and physical activity and chronic disease prevention: Research strategies and recommendations Review uri icon


MeSH Major

  • Chronic Disease
  • Feeding Behavior
  • Motor Activity
  • Nutritional Physiological Phenomena
  • Obesity
  • Primary Prevention


  • A shortage of credible information exists on practical dietary and physical activity patterns that have potential to reverse the national obesity epidemic and reduce the risk of major cancers and other chronic diseases. Securing such information is a challenging task, and there is considerable diversity of opinion concerning related research designs and priorities. Here, we put forward some perspectives on useful methodology and infrastructure developments for progress in this important area, and we list high-priority research topics in the areas of 1) assessment of nutrient intake and energy expenditure; 2) development of intermediate outcome biomarkers; 3) enhancement of cohort and cross-cultural studies; and 4) criteria for and development of full-scale nutrition and physical activity intervention trials.

publication date

  • September 2004



  • Review



  • eng

Digital Object Identifier (DOI)

  • 10.1093/jnci/djh240

PubMed ID

  • 15339966

Additional Document Info

start page

  • 1276

end page

  • 87


  • 96


  • 17