Quantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrier Academic Article uri icon

Overview

MeSH Major

  • DNA Methylation
  • Membrane Transport Proteins
  • Promoter Regions, Genetic
  • RNA, Messenger

abstract

  • This study further suggests that promoter methylation is a potential basis for MTX resistance. The quantitative correlation identified in this study implies that promoter methylation is possibly a mechanism involved in the fine regulation of RFC transcription.

publication date

  • May 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2387170

Digital Object Identifier (DOI)

  • 10.1186/1471-2407-8-124

PubMed ID

  • 18452618

Additional Document Info

start page

  • 124

volume

  • 8