Prognostic implications of the distribution of lymph node metastases in rectal cancer after neoadjuvant chemoradiotherapy Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Lymph Node Excision
  • Lymph Nodes
  • Rectal Neoplasms

abstract

  • Our data suggest that, after preoperative chemoradiotherapy, proximal lymph node involvement is associated with a high incidence of metastatic disease at time of surgery. Because the median number of involved lymph nodes is low after preoperative chemoradiotherapy, the TNM staging system may not provide an accurate assessment of metastatic disease. Therefore, the ypTNM staging system should incorporate distribution as well as number of lymph node metastases after preoperative chemoradiotherapy for rectal cancer.

publication date

  • September 22, 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2007.12.7704

PubMed ID

  • 18362367

Additional Document Info

start page

  • 2106

end page

  • 11

volume

  • 26

number

  • 13