The Memorial Sloan Kettering Cancer Center experience with outpatient administration of high dose methotrexate with leucovorin rescue Academic Article uri icon

Overview

MeSH Major

  • Ambulatory Care
  • Antimetabolites, Antineoplastic
  • Bone Neoplasms
  • Leucovorin
  • Methotrexate
  • Osteosarcoma

abstract

  • Outpatient administration of HDMTX and the required supportive therapy is safe and feasible using the described approach. Approximately half of the patients will require leucovorin dose modification based on serial monitoring of MTX levels.

publication date

  • June 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/pbc.21419

PubMed ID

  • 18266225

Additional Document Info

start page

  • 1176

end page

  • 80

volume

  • 50

number

  • 6