Successful techniques for retaining a cohort of infants and children born to HIV-infected women: The prospective P2C2 HIV study Academic Article uri icon


MeSH Major

  • Caregivers
  • HIV Infections
  • Infectious Disease Transmission, Vertical
  • Reimbursement, Incentive


  • Retaining subjects from disadvantaged populations in long-term studies is necessary to obtain high-quality data. This article presents cumulative retention rates from a 5-year prospective cohort study, the Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection study. It also presents results of a cross-sectional qualitative survey about factors that induced caregivers to stay in the study. Although the repeated study visits were long and uncomfortable, cumulative retention among the 298 HIV-infected children was 80%. Incentives considered important by the caregivers included phone contact with nurse coordinators, nurse coordinators accompanying the caregiver and child during visits, phone reminders for appointments, help with scheduling, meals and transportation, access to health care, and relationships with staff. Thus, the high follow-up rate was in part due to nurses' efforts to reduce the study's burden on the families, provide tangible and intangible incentives, and establish personal relationships with families.

publication date

  • July 2004



  • Academic Article



  • eng

PubMed Central ID

  • PMC4417743

Digital Object Identifier (DOI)

  • 10.1177/1055329003256653

PubMed ID

  • 15296658

Additional Document Info

start page

  • 48

end page

  • 57


  • 15


  • 4