Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: Modulation by sirolimus Academic Article uri icon

Overview

MeSH Major

  • Arginine
  • Heart Transplantation
  • Immunosuppressive Agents
  • Sirolimus
  • Vascular Diseases

abstract

  • Elevated plasma ADMA is associated with coronary intimal hyperplasia, supporting the importance of nitric oxide synthase inhibition in CAV pathogenesis. Treatment with sirolimus (rather than MMF) is associated with lower ADMA levels and reduced risk of accelerated CAV.

publication date

  • March 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/TP.0b013e318166a3a4

PubMed ID

  • 18360263

Additional Document Info

start page

  • 827

end page

  • 33

volume

  • 85

number

  • 6