Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML Academic Article uri icon

Overview

MeSH Major

  • Blast Crisis
  • Cytoskeletal Proteins
  • Hematopoietic Stem Cells
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive
  • Trans-Activators

abstract

  • Activation of beta-catenin in CML granulocyte-macrophage progenitors appears to enhance the self-renewal activity and leukemic potential of these cells.

publication date

  • August 12, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa040258

PubMed ID

  • 15306667

Additional Document Info

start page

  • 657

end page

  • 67

volume

  • 351

number

  • 7