Preoperative therapy in invasive breast cancer: Pathologic assessment and systemic therapy issues in operable disease Review uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Breast Neoplasms
  • Neoadjuvant Therapy

abstract

  • In operable breast cancer, preoperative systemic therapy is effective and can improve breast conservation rates. Unless the tumor is large or the patient is in a clinical trial, postoperative adjuvant systemic therapy is the standard of care. To achieve optimal outcomes, preoperative systemic therapy must be administered as part of a coordinated, multimodality treatment program. The preoperative setting provides a unique opportunity to study the impact of systemic therapies on breast cancer biology.

publication date

  • February 2, 2008

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.2007.15.3510

PubMed ID

  • 18258991

Additional Document Info

start page

  • 814

end page

  • 9

volume

  • 26

number

  • 5