Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: A cross-sectional cohort study Academic Article uri icon

Overview

MeSH Major

  • Cytokines
  • Interleukin-13
  • Pulmonary Disease, Chronic Obstructive

abstract

  • Systemic inflammation in a COPD cohort is characterized by cytokines implicated in inflammatory cell recruitment and airway remodeling. Plasma concentrations of IL-13 and chemoattractants for monocytes, T lymphocytes, and eosinophils show associations with increasing severity of disease. Soluble Fas, G-CSF and CXCL9/Mig may be unique markers that associate with disease characterized by disproportionate abnormalities in DLCO independent of the FEV1.

publication date

  • September 14, 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2064925

Digital Object Identifier (DOI)

  • 10.1186/1465-9921-8-64

PubMed ID

  • 17868461

Additional Document Info

start page

  • 64

volume

  • 8