Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation Academic Article uri icon

Overview

MeSH Major

  • Amidohydrolases
  • Arginine
  • Cerebrovascular Circulation
  • Endothelium, Vascular

abstract

  • These findings provide the first evidence that overexpression of DDAH-1 increases basal levels of vascular NO and protects against ADMA-induced endothelial dysfunction in the cerebral circulation.

publication date

  • January 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/STROKEAHA.107.490631

PubMed ID

  • 18063827

Additional Document Info

start page

  • 180

end page

  • 4

volume

  • 39

number

  • 1