Cytologic malignancy versus benignancy: How useful are the "newer" markers in body fluid cytology? Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Biomarkers, Tumor
  • Body Fluids
  • Epithelium
  • Mesothelioma
  • Pleural Effusion, Malignant

abstract

  • MOC-31 and D2-40 were very sensitive and specific markers of epithelial and mesothelial cells, respectively. Compared with calretinin, D2-40 was a more sensitive marker of mesothelial cells. WT1 proved to be nonspecific. XIAP was not a sensitive marker for malignancy and had a limited value in cytology. We recommend using a panel to include MOC-31 and D2-40 to improve diagnostic accuracy in body cavity effusions.

publication date

  • January 2008

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 18181669

Additional Document Info

start page

  • 23

end page

  • 8

volume

  • 132

number

  • 1