Familial vulnerability to ADHD affects activity in the cerebellum in addition to the prefrontal systems
Academic Article
Overview
MeSH Major
Attention Deficit Disorder with Hyperactivity
Cerebellum
Corpus Striatum
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Prefrontal Cortex
abstract
These findings suggest that activity in both the prefrontal cortex and cerebellum is sensitive to familial vulnerability to ADHD. Unaffected siblings of individuals with ADHD show deficits similar to affected probands in prefrontal areas for unexpected events and in cerebellum for events atunexpected times.