Prognostic significance of transdural invasion of cranial base malignancies in patients undergoing craniofacial resection: Commentary
Cranial Fossa, Anterior
Overall OS and PFS in highly selected patients with transdural invasion of cranial base malignancy is similar to what has been historically reported for patients without such invasion. The most important variables positively affecting OS and PFS seem to be the ability to achieve a microscopically margins-negative resection followed by absence of brain invasion. Performing this resection in a piecemeal fashion does not seem to affect survival outcomes.