Matrix metalloproteinase inhibition attenuates brain edema in an in vivo model of surgically-induced brain injury: Commentary Article uri icon

Overview

MeSH Major

  • Brain Edema
  • Brain Injuries
  • Disease Models, Animal
  • Matrix Metalloproteinase Inhibitors
  • Neurosurgical Procedures

abstract

  • Inhibition of MMP-9 and MMP-2 attenuates brain edema and BBB disruption after SBI. The study suggests a potential role for MMP inhibition as preoperative therapy before neurosurgical procedures.

publication date

  • November 2007

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1227/01.neu.0000303203.07866.18

Additional Document Info

start page

  • 1067

end page

  • 75; discussion 1075-6

volume

  • 61

number

  • 5