Gamma globulin: Unmasking of hidden antigenic sites on light chains Academic Article uri icon

Overview

MeSH Major

  • Antigens
  • Bence Jones Protein
  • Immunodiffusion
  • Multiple Myeloma
  • Peptides
  • Precipitin Tests
  • Research
  • gamma-Globulins

abstract

  • Normal light (L) chains cleaved from normal pooled human gamma globulin contain immunologic determinants not overtly present in the native unreduced molecule. These hidden determinants are shared with Bence Jones proteins. Similarly, one of two Bence Jones proteins contained immunologic determinants which were not overtly present on the autologous serum myeloma protein.

publication date

  • December 1964

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 14171555

Additional Document Info

start page

  • 167

end page

  • 70

volume

  • 145

number

  • 3628