Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system Academic Article Article uri icon

Overview

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • Immunotherapy
  • Neuroimmunomodulation
  • Parkinson Disease
  • T-Lymphocytes, Regulatory

abstract

  • Exacerbations of schizophrenic behavior are associated with elevations of urinary tryptophan metabolites. Free tryptophan and methionine possibly arising from the breakdown of muscle protein may act like an endogenous metabolic factor which enhances behavioral worsening. Some of the apparently spontaneous activations of psychotic symptoms may be intensified by the endogenous liberation of these two compounds.

publication date

  • December 1964

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 14169723

Additional Document Info

start page

  • 311

end page

  • 3

volume

  • 144

number

  • 3616