Nitrosative stress and myocardial sarcoplasmic endoreticular calcium adenosine triphosphatase subtype 2a activity after lung resection in swine Academic Article uri icon

Overview

MeSH Major

  • Lung
  • Myocardium
  • Nitric Oxide
  • Oxidative Stress
  • Sarcoplasmic Reticulum Calcium-Transporting ATPases

abstract

  • These data indicate that oxidative/nitrosative stress associated with lung resection influences SERCA2a activity independent of any influence on protein expression or phospholamban phosphorylation. The findings link an acute event with a subcellular process primarily described for chronic illness and suggest a biochemical basis for perioperative changes in myocardial mechanical reserve.

publication date

  • December 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/01.anes.0000291446.70921.61

PubMed ID

  • 18043064

Additional Document Info

start page

  • 954

end page

  • 62

volume

  • 107

number

  • 6