Malaria: a peek at the var variorum. Review uri icon

Overview

MeSH

  • Animals
  • Evolution, Molecular
  • Humans

MeSH Major

  • Genes, Protozoan
  • Genetic Variation
  • Malaria, Falciparum
  • Plasmodium falciparum

abstract

  • Geneticists encountering the diversity of the malaria parasite's var gene family for the first time often complain that its complexity is a nightmare. A new article by Barry et al. presents the latest and most systematic attempt to date to decipher the var variorum. This important work, combined with other recent articles on var global variation such as that by Kraemer et al., suggests that only the tip of the var diversity iceberg is currently in view. In this article, we discuss these recent results and provide an overview of current understanding of var diversity.

publication date

  • December 2007

has subject area

  • Animals
  • Evolution, Molecular
  • Genes, Protozoan
  • Genetic Variation
  • Humans
  • Malaria, Falciparum
  • Plasmodium falciparum

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.pt.2007.08.022

PubMed ID

  • 17977793

Additional Document Info

start page

  • 563

end page

  • 565

volume

  • 23

number

  • 12