The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without history of a thrombotic event Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Anticardiolipin
  • Granulomatosis with Polyangiitis
  • Pulmonary Embolism
  • Thrombophilia
  • Venous Thrombosis

abstract

  • Although the incidence of clinically significant VTE is increased in patients with WG, this increased risk is not explained by increased prevalences of aCL, anti-beta2-GP, FVL, or mutations in PGM or MTHFR. These observations suggest a need to search for new genetic or acquired prothrombotic abnormalities to account for the increased thrombotic event rate in patients with active WG.

publication date

  • December 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 17918782

Additional Document Info

start page

  • 2446

end page

  • 50

volume

  • 34

number

  • 12