Proliferative changes in the bronchial epithelium of former smokers treated with retinoids. Academic Article uri icon

Overview

MeSH Major

  • Anticarcinogenic Agents
  • Bronchi
  • Isotretinoin
  • Respiratory Mucosa
  • Smoking
  • Smoking Cessation
  • Tretinoin
  • alpha-Tocopherol

abstract

  • In per-subject analyses, treatment with 13-cis-RA and alpha-tocopherol, compared with placebo, was statistically significantly associated with reduced bronchial epithelial cell proliferation; treatment with 9-cis-RA was not. In per-site analyses, statistically significant associations were obtained with both treatments.

publication date

  • November 7, 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC3441140

Digital Object Identifier (DOI)

  • 10.1093/jnci/djm205

PubMed ID

  • 17971525

Additional Document Info

start page

  • 1603

end page

  • 12

volume

  • 99

number

  • 21