Sleep disorder as a clinical risk factor of major depression: associated with cognitive impairment. Academic Article uri icon

Overview

abstract

  • BACKGROUND: This research aims explored the sleep disorder (SD) role in major depressive disorder (MDD), and the SD influencing their cognition. METHODS: 372 MDD patients and 457 healthy controls (HCs) were enrolled. RESULTS: Patients increased a 38.88 times SD risk compared with HCs. In patients, visuospatial/constructional score was lower in SD than non-SD, and PSQI score was negatively associated with visuospatial/constructional score of SD. In SD and non-SD, RBANS scores were lower in MDD than HCs, excepted for visuospatial/constructional in non-SD. CONCLUSION: The SD as a MDD risk factor, has more serious visuospatial/constructional impairment alleviated via improving sleep/depression in patients.

publication date

  • August 9, 2022

Research

keywords

  • Cognitive Dysfunction
  • Depressive Disorder, Major
  • Sleep Wake Disorders

Identity

Digital Object Identifier (DOI)

  • 10.1016/j.ajp.2022.103228

PubMed ID

  • 35973338

Additional Document Info

volume

  • 76