Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections. Academic Article uri icon

Overview

abstract

  • Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of infection for BA.2. Natural immunity from previous infection and booster vaccination were associated with less infectious breakthrough infections.

authors

  • Qassim, Suelen
  • Chemaitelly, Hiam Souheil
  • Ayoub, Houssein H
  • AlMukdad, Sawsan
  • Tang, Patrick
  • Hasan, Mohammad R
  • Yassine, Hadi M
  • Al-Khatib, Hebah A
  • Smatti, Maria K
  • Abdul-Rahim, Hanan F
  • Nasrallah, Gheyath K
  • Al-Kuwari, Mohamed Ghaith
  • Al-Khal, Abdullatif
  • Coyle, Peter
  • Kaleeckal, Anvar Hassan
  • Shaik, Riyazuddin Mohammad
  • Latif, Ali Nizar
  • Al-Kuwari, Einas
  • Jeremijenko, Andrew
  • Butt, Adeel A
  • Bertollini, Roberto
  • Al-Romaihi, Hamad Eid
  • Al-Thani, Mohamed H
  • Abu-Raddad, Laith Jamal

publication date

  • May 27, 2022

Research

keywords

  • COVID-19

Identity

Digital Object Identifier (DOI)

  • 10.1093/jtm/taac068

PubMed ID

  • 35639932