Oncolysis by viral replication and inhibition of angiogenesis by a replication-conditional herpes simplex virus that expresses mouse endostatin Academic Article uri icon

Overview

MeSH Major

  • Colonic Neoplasms
  • Endostatins
  • Genetic Therapy
  • Herpesvirus 1, Human
  • Neovascularization, Pathologic
  • Virus Replication

abstract

  • The oncolytic HSV-1 mutant HSV-Endo provided a two-pronged therapy; namely, inhibition of angiogenesis and direct tumor cell destruction by viral replication.

publication date

  • August 15, 2004

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncr.20434

PubMed ID

  • 15305421

Additional Document Info

start page

  • 869

end page

  • 77

volume

  • 101

number

  • 4