Retinoblastoma patients with high risk ocular pathological features: Who needs adjuvant therapy?
Antineoplastic Combined Chemotherapy Protocols
Relapsing patients can be rescued with intensive therapy. Those with isolated choroidal or PLONI have a good prognosis without adjuvant therapy. Patients with PLONI with a positive margin have a good prognosis if treated with combined therapy. Those with scleral involvement or PLONI with concomitant choroid disease may benefit from adjuvant therapy.