Recurrent ependymoma treated with high-dose tamoxifen in a peripubertal female: Impact on tumor and the pituitary-ovarian axis Academic Article uri icon

Overview

MeSH Major

  • Ependymoma
  • Ovarian Cysts
  • Tamoxifen

abstract

  • Due to high rates of recurrence, the prognosis of childhood ependymoma remains guarded. Anecdotal evidence suggests that tamoxifen may have a role in the treatment of these tumors. We present a case of a child with recurrent ependymoma treated with tamoxifen who showed tumor regression on two separate occasions. However, treatment with tamoxifen resulted in the development of large ovarian cysts associated with supraphysiological plasma concentrations of estradiol.

publication date

  • October 15, 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/pbc.20647

PubMed ID

  • 16261561

Additional Document Info

start page

  • 758

end page

  • 60

volume

  • 49

number

  • 5