Finasteride and high-grade prostate cancer in the prostate cancer prevention trial Academic Article uri icon

Overview

MeSH Major

  • Anticarcinogenic Agents
  • Enzyme Inhibitors
  • Finasteride
  • Prostatic Neoplasms

abstract

  • Effects of finasteride on prostate volume and selective inhibition of low-grade cancer, rather than effects on tumor morphology, may have contributed to the increase in high-grade cancers with finasteride in the PCPT. Although induction of high-grade cancer cannot be excluded, the results suggest that high-grade cancer was detected earlier and was less extensive in the finasteride group than in the placebo group.

publication date

  • September 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/jnci/djm117

PubMed ID

  • 17848673

Additional Document Info

start page

  • 1375

end page

  • 83

volume

  • 99

number

  • 18