Concurrent Chemotherapy and Intensity-Modulated Radiotherapy for Locoregionally Advanced Laryngeal and Hypopharyngeal Cancers Academic Article uri icon

Overview

MeSH Major

  • Hypopharyngeal Neoplasms
  • Laryngeal Neoplasms
  • Radiotherapy, Intensity-Modulated

abstract

  • These preliminary results have shown that IMRT achieved encouraging locoregional control of locoregionally advanced laryngeal and hypopharyngeal carcinomas. Xerostomia improved over time. Pharyngoesophageal stricture with percutaneous endoscopic gastrostomy dependency remains a problem, particularly for patients with hypopharyngeal carcinoma and, to a lesser extent, those with laryngeal cancer. Strategies using IMRT to limit the dose delivered to the esophagus/inferior constrictor musculature without compromising target coverage might be useful to further minimize this late complication.

publication date

  • October 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ijrobp.2007.03.013

PubMed ID

  • 17493769

Additional Document Info

start page

  • 459

end page

  • 68

volume

  • 69

number

  • 2