Comparison of first-line with second-line antibiotics for acute exacerbations of chronic bronchitis: A metaanalysis of randomized controlled trials Review uri icon

Overview

MeSH Major

  • Bronchitis, Chronic
  • Macrolides
  • Penicillins

abstract

  • Compared to first-line antibiotics, second-line antibiotics are more effective, but not less safe, when administered to patients with AECB. The available data did not allow for stratified analyses according to the presence of risk factors for poor outcome, such as increased age, impaired lung function, airway obstruction, and frequency of exacerbations; this fact should be taken into consideration when interpreting the findings of this metaanalysis.

publication date

  • January 2007

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1378/chest.07-0149

PubMed ID

  • 17573508

Additional Document Info

start page

  • 447

end page

  • 55

volume

  • 132

number

  • 2