Anti-MAG/SGPG associated neuropathy does not commonly cause distal nerve temporal dispersion Academic Article uri icon

Overview

MeSH Major

  • Action Potentials
  • Muscle, Skeletal
  • Myelin-Associated Glycoprotein
  • Polyneuropathies

abstract

  • Patients with anti-myelin associated glycoprotein (anti-MAG) neuropathy have uniform slowing without temporal dispersion, but do usually have disproportionately distal slowing. We evaluated distal compound muscle action potential (CMAP) dispersion in 29 patients with anti-MAG/sulphated glucuronyl paragloboside (SGPG) neuropathy (titres > or = 12,800). Among 138 motor responses, 15% (tibial), 7.3% (peroneal), 10.7% (median) and 13.8% (ulnar) had distal CMAP duration > 9 ms. Disproportionate distal slowing with normal distal CMAP duration in the arms may be useful to differentiate chronic inflammatory demyelinating polyneuropathy from anti-MAG/SGPG associated neuropathy.

publication date

  • August 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2117731

Digital Object Identifier (DOI)

  • 10.1136/jnnp.2006.111930

PubMed ID

  • 17353253

Additional Document Info

start page

  • 902

end page

  • 4

volume

  • 78

number

  • 8