CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia Academic Article uri icon

Overview

MeSH Major

  • Antigens, CD
  • Apyrase
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Platelet Activation

abstract

  • CD39 is expressed and active on CLL cells. Enzyme activity is higher in earlier stages of CLL and decreased enzyme activity may be associated with worsening disease. These results suggest that CD39 may play a role in the pathogenesis of malignancy and protect CLL patients from thrombotic events.

publication date

  • May 4, 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC1885243

Digital Object Identifier (DOI)

  • 10.1186/1479-5876-5-23

PubMed ID

  • 17480228

Additional Document Info

start page

  • 23

volume

  • 5