Genetic testing to identify high-risk populations for chemoprevention studies. Review uri icon

Overview

MeSH

  • Clinical Trials as Topic
  • Genetic Predisposition to Disease
  • Genetic Techniques
  • Haplotypes
  • Humans
  • Polymorphism, Single Nucleotide
  • Risk Factors

MeSH Major

  • Chemoprevention
  • Genetic Testing
  • Neoplasms

abstract

  • Human genetic variation data is now publicly available on a large scale, from both public and private discovery efforts. Datasets from the International Haplotype Map Consortium and Perlegen Sciences provide a level of knowledge about human genetic variation that is unprecedented. In combination with novel high-throughput genotyping technologies, these new resources will allow cancer prevention investigators to identify in a more precise way which genetic subsets of patients are likely to benefit most from chemoprevention and screening interventions.

publication date

  • 2007

has subject area

  • Chemoprevention
  • Clinical Trials as Topic
  • Genetic Predisposition to Disease
  • Genetic Techniques
  • Genetic Testing
  • Haplotypes
  • Humans
  • Neoplasms
  • Polymorphism, Single Nucleotide
  • Risk Factors

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

PubMed ID

  • 17611307

Additional Document Info

start page

  • 163

end page

  • 168

volume

  • 3

number

  • 3