Anti-adipogenic action of pitavastatin occurs through the coordinate regulation of PPARĪ³ and Pref-1 expression Academic Article uri icon

Overview

MeSH Major

  • Adipocytes
  • Enzyme Inhibitors
  • Intercellular Signaling Peptides and Proteins
  • PPAR gamma
  • Quinolines

abstract

  • Our data suggest that pitavastatin inhibits adipocyte differentiation by blocking PPARgamma expression and activating pref-1 expression. These studies may have implications in the regulation of adipogenesis in response to statins.

publication date

  • July 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2014134

Digital Object Identifier (DOI)

  • 10.1038/sj.bjp.0707250

PubMed ID

  • 17549051

Additional Document Info

start page

  • 807

end page

  • 15

volume

  • 151

number

  • 6