L-arginine supplementation in peripheral arterial disease: No benefit and possible harm Academic Article uri icon

Overview

MeSH Major

  • Arginine
  • Peripheral Vascular Diseases

abstract

  • In patients with PAD, long-term administration of L-arginine does not increase nitric oxide synthesis or improve vascular reactivity. Furthermore, the expected placebo effect observed in studies of functional capacity was attenuated in the L-arginine-treated group. As opposed to its short-term administration, long-term administration of L-arginine is not useful in patients with intermittent claudication and PAD.

publication date

  • July 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/CIRCULATIONAHA.106.683656

PubMed ID

  • 17592080

Additional Document Info

start page

  • 188

end page

  • 95

volume

  • 116

number

  • 2