ANCA Are Detectable in Nearly All Patients with Active Severe Wegener's Granulomatosis Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Antineutrophil Cytoplasmic
  • Granulomatosis with Polyangiitis

abstract

  • ANCA are detectable in nearly all patients with active severe Wegener's granulomatosis, but approximately 1 of 5 patients with active limited disease are ANCA negative. Immunofluorescence and both direct and capture ELISAs are required for optimal detection, suggesting that ANCA are not recognized equally well by all testing methods.

publication date

  • July 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.amjmed.2006.08.016

PubMed ID

  • 17602941

Additional Document Info

start page

  • 643.e9

end page

  • 14

volume

  • 120

number

  • 7