Early ribavirin pharmacokinetics, HCV RNA and alanine aminotransferase kinetics in HIV/HCV co-infected patients during treatment with pegylated interferon and ribavirin> Academic Article uri icon

Overview

MeSH Major

  • Antiviral Agents
  • HIV Infections
  • Hepatitis C, Chronic
  • Interferon-alpha
  • Ribavirin

abstract

  • We conjecture that intracellular ribavirin accumulation may be enhanced early in treatment in coinfected sustained responders, although this hypothesis should be investigated further. At week 1, serum HCV RNA and changes in alanine aminotransferase levels relative to baseline might identify likely responders.

publication date

  • July 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC1994717

Digital Object Identifier (DOI)

  • 10.1016/j.jhep.2007.01.027

PubMed ID

  • 17412448

Additional Document Info

start page

  • 23

end page

  • 30

volume

  • 47

number

  • 1