Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN Academic Article uri icon

Overview

MeSH Major

  • Capillary Permeability
  • Endothelial Cells
  • Intracellular Signaling Peptides and Proteins
  • Lysophospholipids
  • PTEN Phosphohydrolase
  • Protein-Serine-Threonine Kinases
  • Receptors, G-Protein-Coupled
  • Receptors, Lysosphingolipid
  • Signal Transduction
  • Sphingosine

abstract

  • S1P2R activation in endothelial cells increases vascular permeability. The balance of S1P1 and S1P2 receptors in the endothelium may determine the regulation of vascular permeability by S1P.

publication date

  • June 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/ATVBAHA.107.143735

PubMed ID

  • 17431187

Additional Document Info

start page

  • 1312

end page

  • 8

volume

  • 27

number

  • 6