Administration of antibiotics via the respiratory tract for the prevention of ICU-acquired pneumonia: A meta-analysis of comparative trials Review uri icon

Overview

MeSH Major

  • Anti-Bacterial Agents
  • Clinical Trials as Topic
  • Cross Infection
  • Intensive Care Units
  • Pneumonia

abstract

  • The limited available evidence supports that prophylactic administration of antibiotics via the respiratory tract is associated with reduction of occurrence of ICU-acquired pneumonia. However, there is evidence from non-comparative studies that this preventive strategy may lead to an increase in the emergence of resistant bacteria. Thus, further investigation, at least in ICU patients at high risk for development of ICU-acquired pneumonia is warranted, including a more systematic evaluation of issues related to the emergence of resistance.

publication date

  • August 25, 2006

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC1750990

Digital Object Identifier (DOI)

  • 10.1186/cc5032

PubMed ID

  • 16934148

Additional Document Info

start page

  • R123

volume

  • 10

number

  • 4