Evaluation of an Online Platform for Cancer Patient Self-reporting of Chemotherapy Toxicities Academic Article uri icon


MeSH Major

  • Antineoplastic Agents
  • Neoplasms
  • Online Systems
  • Self Care


  • The current mechanism for monitoring toxicity symptoms in cancer trials depends on a complex paper-based process. Electronic collection of patient-reported outcomes (PROs) may be more efficient and accurate. An online PRO platform was created including a simple data entry interface, real-time report generation, and an alert system to e-mail clinicians when patients self-report serious toxicities. Feasibility assessment involving 180 chemotherapy patients demonstrated high levels of use at up to 40 follow-up clinic visits per patient over 16 months (85% of patients at any given visit), with high levels of patient and clinician acceptance and satisfaction (>95%). Alerts were used as the basis for delayed chemotherapy treatments, dose modifications, and scheduling changes. These results demonstrate that online patient-reporting is a feasible strategy for chemotherapy toxicity symptom monitoring, and may improve safety and satisfaction with care. Ongoing multi-center research will evaluate the impact of this approach on clinical and administrative outcomes.

publication date

  • May 2007



  • Academic Article



  • eng

PubMed Central ID

  • PMC2244885

Digital Object Identifier (DOI)

  • 10.1197/jamia.M2177

PubMed ID

  • 17329732

Additional Document Info

start page

  • 264

end page

  • 8


  • 14


  • 3