The potential of ferumoxytol nanoparticle magnetic resonance imaging, perfusion, and angiography in central nervous system malignancy: A pilot study - Commentary Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Ferrosoferric Oxide
  • Gadolinium DTPA
  • Image Enhancement
  • Magnetic Resonance Angiography

abstract

  • Our most important finding was that gadolinium leaks out of blood vessels early after injection, whereas ferumoxytol stays intravascular in the "early" phase, thereby increasing the accuracy of tumor perfusion assessment. As a magnetic resonance imaging contrast agent, ferumoxytol visualizes brain tumors at all field strengths evaluated, with delayed enhancement peaking at 24 to 28 hours after administration.

publication date

  • April 2007

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1227/01.NEU.0000255350.71700.37

Additional Document Info

start page

  • 601

end page

  • 11; discussion 611-2

volume

  • 60

number

  • 4