Assessment of erlotinib pharmacodynamics in tumors and skin of patients with head and neck cancer Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Squamous Cell
  • Head and Neck Neoplasms
  • Quinazolines
  • Skin

abstract

  • The feasibility of obtaining serial evaluable biopsies of HNSCC was suboptimal. Nevertheless, erlotinib inhibited p-EGFR in HNSCC tumors, which appeared associated to clinical benefit, and induced p27 in biopsies of normal skin.

publication date

  • April 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1093/annonc/mdl495

PubMed ID

  • 17317676

Additional Document Info

start page

  • 761

end page

  • 7

volume

  • 18

number

  • 4