Vascular targeted therapy with anti-prostate-specific membrane antigen monoclonal antibody J591 in advanced solid tumors
Academic Article
Overview
MeSH Major
Antibodies, Monoclonal
Antigens, Neoplasm
Antigens, Surface
Antineoplastic Agents
Glutamate Carboxypeptidase II
Neoplasms
Neovascularization, Pathologic
abstract
Acceptable toxicity and excellent targeting of known sites of metastases were demonstrated in patients with multiple solid tumor types, highlighting a potential role for the anti-PSMA antibody J591 as a vascular-targeting agent.
