High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: Broad implications for immunotherapy Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Anti-Idiotypic
  • Antibodies, Monoclonal
  • Cyclophosphamide
  • Immunoglobulin G
  • Immunosuppressive Agents
  • Immunotherapy
  • Neuroblastoma
  • Transplantation Conditioning

abstract

  • HD-Cy reliably blocks humoral responses to a murine antibody. This capacity to prevent host rejection of foreign or not fully humanized proteins raises the possibility of a broad role for HD-Cy in immunotherapeutic strategies.

publication date

  • April 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/pbc.20765

PubMed ID

  • 16421906

Additional Document Info

start page

  • 430

end page

  • 4

volume

  • 48

number

  • 4