Setting the bar in phase II trials: The use of historical data for determining "go/no go" decision for definitive phase III testing Review uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Clinical Trials, Phase II as Topic
  • Clinical Trials, Phase III as Topic
  • Medical Oncology
  • Neoplasms
  • Randomized Controlled Trials as Topic
  • Research Design

abstract

  • Many phase II trials require historical data to determine null response rates. Simple guidelines may improve design and reporting of such trials.

publication date

  • February 2007

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC2529160

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-06-0909

PubMed ID

  • 17277252

Additional Document Info

start page

  • 972

end page

  • 6

volume

  • 13

number

  • 3