Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Hepatocellular
  • Genes, Neoplasm
  • Liver Neoplasms
  • Transcription, Genetic

abstract

  • These results have furthered our understanding of the genetic diversity of human HCC and have provided specific identifiers for classifying tumors. In addition, our classification has potential therapeutic implications because 50% of the tumors were related to WNT or AKT pathway activation, which potentially could be targeted by specific inhibiting therapies.

publication date

  • January 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/hep.21467

PubMed ID

  • 17187432

Additional Document Info

start page

  • 42

end page

  • 52

volume

  • 45

number

  • 1