Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia Academic Article uri icon

Overview

MeSH Major

  • Antifungal Agents
  • Fluconazole
  • Itraconazole
  • Mycoses
  • Neutropenia
  • Opportunistic Infections
  • Triazoles

abstract

  • In patients undergoing chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome, posaconazole prevented invasive fungal infections more effectively than did either fluconazole or itraconazole and improved overall survival. There were more serious adverse events possibly or probably related to treatment in the posaconazole group. (ClinicalTrials.gov number, NCT00044486 [ClinicalTrials.gov].).

publication date

  • January 25, 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJMoa061094

PubMed ID

  • 17251531

Additional Document Info

start page

  • 348

end page

  • 59

volume

  • 356

number

  • 4