Outcome of metastatic GIST in the era before tyrosine kinase inhibitors
Gastrointestinal Stromal Tumors
Protein Kinase Inhibitors
Treatment with imatinib appears to improve 2-year survival of metastatic GIST by approximately 20% when compared to surgery alone. The combination of imatinib and surgery for the treatment of metastatic GIST therefore warrants investigation.