Genetic polymorphisms of the platelet receptors P2Y12, P2Y1 and GP IIIa and response to aspirin and clopidogrel Academic Article uri icon

Overview

MeSH Major

  • Aspirin
  • Integrin beta3
  • Platelet Aggregation Inhibitors
  • Polymorphism, Genetic
  • Receptors, Purinergic P2
  • Ticlopidine

abstract

  • We did not find an association between polymorphisms in the platelet receptors GP IIIa, P2Y(12) or P2Y(1) and response to aspirin or clopidogrel in cardiac patients. These findings suggest that the variability in response to anti-platelet drugs is multi-factorial and is not caused only by single gene mutations.

publication date

  • January 2007

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.thromres.2006.02.006

PubMed ID

  • 16581111

Additional Document Info

start page

  • 355

end page

  • 60

volume

  • 119

number

  • 3