Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis Academic Article uri icon

Overview

MeSH Major

  • Genes, p53
  • Polymorphism, Single Nucleotide
  • Receptor, Fibroblast Growth Factor, Type 4
  • Urinary Bladder Neoplasms

abstract

  • The impact of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism on bladder cancer is unknown. We found no clear correlations between the FGFR4 genotype and risk of bladder cancer or pathological parameters. Neither the polymorphism nor TP53 mutation status was an independent predictor of prognosis, but they might act jointly on the disease-specific survival of patients.

publication date

  • December 4, 2006

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2360734

Digital Object Identifier (DOI)

  • 10.1038/sj.bjc.6603456

PubMed ID

  • 17088904

Additional Document Info

start page

  • 1455

end page

  • 8

volume

  • 95

number

  • 11